Commanding officer: Lt.Colonel Henry M.Beckley, 1863 – 64
Major Blake Lynch Woodson, 1864-65
The six companies were recruited mainly from Boone, Cabell, Logan, McDowell, Wayne, Wyoming, and Pike Counties. Beckley served in the 1st Virginia State Line.
When he learned of the disbandment of that organization in January, 1863, Beckley started forming the 45th. Beckley´s command was officially recognized in December, 1863. The unit skirmished partly in the Tug and Guyandotte valleys but also fought regularly.
Beckley was taken prisoner in September 1864 at Winchester, Virginia. He spent the rest of the war in Federal prison camp. Woodson (b. 1835) after the war retired to his Lynchburg home moving to Kansas City, Missouri, in 1871, where he practiced law. Passing away 1902 he is buried at Forest Hill Cemetery.